Nutritional Supplements to Support Your Brain*

This page brings together our most common supplement recommendations for patients and clients: which supplements to STOP taking and which to START taking.

For each recommended supplement, you’ll find a brief explanation of why we recommend it and where to order it. We select these products for their quality and value, even when less expensive options are available.

We offer a 20% discount off the suggested retail price through Fullscript for many of the supplements listed here.

Create a free Fullscript account or log in to your existing account, then search for the products you would like to order.

STOP

STOP taking iron supplements. Our bodies meet most of their daily iron needs by recycling iron already present in the body. We usually don’t need iron from supplements; supplemental iron can cause problems. 

STOP taking vitamin D3. Vitamin D supplements are the storage form of vitamin D, not the form produced through sunlight exposure. They can interfere with the absorption of other vitamins and interfere with your ability to produce clean energy.

STOP taking calcium supplements. Calcium supplements often lead to iron buildup, which weakens the bone-building cells that help keep your bones strong. They can also block magnesium absorption and make it harder for your brain to create clean, efficient energy.

STOP taking zinc supplements. Dietary zinc is fine, but zinc supplements are not. Zinc supplements can block an important enzyme that recycles iron from a harmful state into one that does not cause oxidative stress or free-radical damage.

STOP using ascorbic acid, citrate, and citric acid. They often interfere with ceruloplasmin, one of the body’s most important proteins and enzyme complexes. Real vitamin C from whole foods supports the body’s enzyme systems.

STOP using industrialized omega-6 oils such as soybean, canola, safflower, and corn oils. They are highly reactive, prone to free-radical damage, and can increase oxidative stress in your brain.

Supplements to Support Your Brain

Liquid Ionic Trace Minerals — Bio-Design

Why I recommend this:
Minerals fall into two broad categories: macrominerals and trace minerals. Trace minerals are essential for many body functions, including enzyme activity, normal growth and development, neurological function, antioxidant defenses, healthy blood formation, and hormone production.

Suggested use: Add ½ teaspoon of liquid trace minerals to ½ gallon (64 ounces) of pure, filtered, non-fluoridated water and sip throughout the day.

Where to buy: Trace mineral drops are available at many health food stores. I recommend Liquid Ionic Trace Minerals by Bio-Design, available through Fullscript.

Adrenal Cocktail — Jigsaw Health

Why I recommend this:
Chronic stress can impair adrenal function over time, affecting cortisol and aldosterone, which may in turn affect potassium levels. This may contribute to persistent fatigue, a feeling of “hitting the wall” energetically, and sometimes anxiety, low mood, or poor sleep.

Many do-it-yourself Adrenal Cocktail recipes are available and typically provide approximately 375 mg of potassium, 460 mg of sodium, and 60 mg of whole-food vitamin C. I recommend Jigsaw Health’s Adrenal Cocktail as a convenient premade option.

Suggested use: 6 capsules or 1 scoop per day.

Where to buy: Fullscript

Vitamin Code RAW Vitamin C — Garden of Life

Note: Jigsaw Health Adrenal Cocktail contains whole-food vitamin C, so this product may be redundant if you are already taking the Adrenal Cocktail.

Why I recommend this:
Many inexpensive vitamin C supplements rely mainly on ascorbic acid and don't include the broader range of naturally occurring compounds found in whole-food sources of vitamin C. Whole-food sources of vitamin C provide a broader range of naturally occurring nutrients that support normal cellular energy production.*

Suggested use: 1 capsule twice a day.

Where to buy: Fullscript

Rosita’s Cod Liver Oil

Why I recommend this:
Like regular fish oil, cod liver oil is high in omega-3 fatty acids, which support your heart, skin, and brain.* Cod liver oil is also high in naturally occurring vitamins A and D, giving it an especially nutritious profile.*

Rosita’s Cod Liver Oil contains natural forms of vitamins A and D in a healthy ratio, with approximately ten times more vitamin A than vitamin D.

Suggested use: 1 teaspoon per day (or 2–3 capsules per day).

Where to buy: Fullscript

Magnesium Glycinate, 120 mg — Pure Encapsulations

Why I recommend this:
Magnesium supports cellular energy production, neurological function, muscle and cardiovascular health, relaxation, and sleep.*

Magnesium glycinate is a well-absorbed form of magnesium that is often easier on the digestive system than other forms.

Suggested use: 1–3 capsules daily, or as directed.

Where to buy: Fullscript

Copper Bisglycinate — Thorne Research

Why I recommend this:
Copper is an essential element that helps manage iron and oxygen and supports clean, efficient energy production in your body and brain.

Suggested use: 1 capsule per day.

Where to buy: Fullscript

Vitamin A, 3,000 mcg — Pure Encapsulations

Note: The best sources of vitamin A are cod liver oil or organic liver. If you can't find or don't like either of those, then use this product as a substitute.

Why I recommend this:
Vitamin A is an essential nutrient that supports healthy immune function, cellular health, vision, and antioxidant defenses. Vitamin A works together with copper and other nutrients to ensure clean energy for your body and brain.

Suggested use: 1 capsule per day or as directed.

Where to buy: Fullscript

Vitamin E — Dr. Mercola Premium Products

Why I recommend this:
Your brain is made up of a high percentage of fat, and vitamin E plays an important role in limiting lipid peroxidation, or oxidative damage to fats in the brain.

This vitamin E product contains a broader spectrum of tocopherols and tocotrienols. Many vitamin E supplements, by contrast, contain only or mainly alpha-tocopherol.

Suggested use: 1 capsule per day.

Where to buy: Fullscript

Vitamin K — Thorne

Why I recommend this:
Vitamin K works in tandem with other fat-soluble vitamins. It supports neurological health and helps direct calcium toward bones and away from arteries.

Suggested use: 2 capsules per day.

Where to buy: Fullscript

Vitamin B Complex — Dr. Mercola

Why I recommend this:
Your brain has exceptionally high energy requirements, and B vitamins play essential roles in the biochemical pathways your cells use to produce energy.

Most B vitamins are water-soluble and need regular intake. Because the B vitamins work together in many metabolic pathways, I generally prefer a well-balanced B-complex rather than relying on individual B vitamins alone.

I also prefer formulations that provide carefully selected forms and amounts of the individual B vitamins rather than unnecessarily high doses.

Suggested use: 1 capsule in the morning and 1 capsule in the evening.

Where to buy: Amazon

NeuroFlam — Apex Energetics

Why I recommend this:
NeuroFlam contains botanical compounds and phytonutrients selected to support a healthy inflammatory response and normal neurological function.*

I sometimes recommend NeuroFlam for people who experience brain fog, reduced cognitive endurance, or other symptoms that may accompany excessive inflammatory activity.

Suggested use: 2–4 capsules per day, or as directed.

Where to buy: Fullscript

NeuroO2 — Apex Energetics

Why I recommend this:
NeuroO2 combines herbs and nutrients intended to support healthy circulation, oxygen utilization, cellular energy production, and neurological function.

Suggested use: Follow the recommended dose.

Where to buy: Fullscript

Supplements to Support Your Digestion

Healthy digestion is closely connected with nutritional status, immune function, and overall neurological health. These are several products I commonly use to support gastrointestinal function.

ION Gut Support — Intelligence of Nature

Why I recommend this:
ION Gut Support contains humic substances designed to support the integrity of the intestinal barrier and a healthy gastrointestinal environment.*

I sometimes recommend it for people who experience frequent food sensitivities, digestive irritation, brain fog, or reduced cognitive endurance.

Suggested use: 1 teaspoon 1–3 times daily, or as directed.

Where to buy: Fullscript

EnteroVite — Apex Energetics

Why I recommend this:
EnteroVite provides short-chain fatty acids and other nutrients that support intestinal cells, the gut microbiome, and normal gastrointestinal barrier function.*

Short-chain fatty acids also play important roles in communication between the digestive and nervous systems.

Suggested use: 2–3 capsules twice daily, or as directed.

Where to buy: Fullscript

Multi-Enzyme — Thorne

Why I recommend this:
Normal digestive enzyme production can change with age, stress, diet, and gastrointestinal health. Supplemental digestive enzymes can help support normal digestion and nutrient absorption.*

Suggested use: 1–2 capsules with meals.

Where to buy: Fullscript

Gastro ULC — Apex Energetics

Why I recommend this:
Gastro ULC contains nutrients and botanical ingredients designed to support the stomach lining and normal gastrointestinal comfort.*

I sometimes use it when additional support for the upper digestive tract or stomach lining is appropriate.

Suggested use: 1–2 capsules daily, or as directed.

Where to buy: Fullscript

BileMin — Apex Energetics

Why I recommend this:
Bile production and flow are important for digestion, particularly the digestion and absorption of fats and fat-soluble nutrients.

BileMin supports normal bile function, digestion, and the body’s natural liver and detoxification processes.*

Suggested use: 1–2 capsules daily, or as directed.

Where to buy: Fullscript

Supplements to Support a Healthy Inflammatory Response

NeuroFlam — Apex Energetics

Note: NeuroFlam is also listed in the Supplements to Support Your Brain section above.

It contains botanical compounds and phytonutrients selected to support a healthy inflammatory response and normal neurological function.*

Where to buy: Fullscript

Trizomal Glutathione — Apex Energetics

Why I recommend this:
Glutathione is one of the body’s most important naturally produced antioxidants. It plays a central role in protecting cells from oxidative stress and supporting normal liver and immune function.*

Because the brain has particularly high energy requirements, maintaining healthy antioxidant defenses is especially important for neurological health.

Trizomal Glutathione provides multiple forms of glutathione designed to support healthy glutathione levels and antioxidant activity.*

Suggested use: 1–2 teaspoons per day.

Where to buy: Fullscript

Glutathione Recycler — Apex Energetics

Why I recommend this:
Your body continuously produces, uses, and recycles glutathione. Glutathione also works alongside other antioxidants, including vitamins C and E, as part of the body’s antioxidant defense system.

Aging, illness, nutritional status, and increased physiological stress may affect the body’s ability to maintain optimal glutathione status.

Glutathione Recycler provides nutrients intended to support your body’s natural glutathione production and recycling.*

Suggested use: 1 capsule 2–3 times daily.

Where to buy: Fullscript

DMSO Liquid or Gel — Five Star Materials Resources

Why I recommend this:
DMSO is a topical compound sometimes used to reduce inflammation following musculoskeletal stress or injury.

DMSO penetrates the skin readily and can increase the absorption of substances present on the skin. For this reason, apply it only to thoroughly clean skin and use it carefully.

Liquid DMSO absorbs quickly, while the gel may be easier to apply to a localized area.

Suggested use: Apply a small amount to clean skin over the desired area. If you experience skin irritation, stop using it and discuss it with your healthcare practitioner.

Where to buy: Amazon

Neprinol AFD — Arthur Andrew Medical

Why I recommend this:
Neprinol AFD contains a combination of proteolytic and fibrinolytic enzymes intended to support healthy circulation and a balanced inflammatory response.*

Because products containing systemic enzymes may not be appropriate for everyone—particularly people taking medications that affect blood clotting—please discuss their use with your healthcare practitioner.

Suggested use: 2 capsules per day on an empty stomach, or as directed.

Where to buy: Fullscript

Manganese Picolinate, 20 mg — Ecological Formulas/Cardiovascular Research

Why I recommend this:
Manganese, along with other trace minerals discussed in the Supplements to Support Your Brain section above, plays an important role in your connective tissue and joint health.

Suggested use: 1 capsule per week.

Where to buy: Fullscript


* The recommendations on this page are for general educational purposes only. If you are preparing for surgery, taking prescription medication, or being treated for a medical condition, consult an appropriate healthcare practitioner before beginning a new supplement.

Affiliate Links: Some Fullscript links on this page are affiliate links. If you make a purchase through one of these links, you will receive a discounted price of 20% below retail cost, and BrainTime may receive a small commission at no additional cost to you.

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